Skip to main content

Table 1 Baseline patient demographics and disease characteristics

From: Anti-PD-1 antibody in combination with radiotherapy as first-line therapy for unresectable intrahepatic cholangiocarcinoma

Characteristics

Patients (N=36)

Age, years

62 (28-75)

Sex

 

 Male

23 (63.9)

 Female

13 (36.1)

ECOG performance status

 

 0

28 (77.8)

 1

8 (22.2)

Type of tumor

 

 Primary

24 (66.7)

 Recurrent

12 (33.3)

Size of primary tumor, cm

 

 ≤5

14 (38.9)

 >5

22 (61.1)

Lymph node status

 

 Negative

14 (38.9)

 Positive

22 (61.1)

TNM stage

 

 II

3 (8.3)

 III

33 (91.7)

CEA, ng/mL

4 (1-25)

CA19-9, ng/mL

1243 (2->12,000)

TMB status

 

 High

15 (41.7)

 Low

21 (58.3)

PD-L1 result

 

 Negative

30 (83.3)

 Positive

6 (16.7)

Microsatellite status

 

 MSI

4 (11.1)

 MSS

32 (88.9)

Multifocal lesions

 

 Single

20 (55.6)

 Multiple

16 (44.4)

Albumin, g/L

36 (28-49)

TBIL, μmol/L

14.3 (3.5-33.0)

Cirrhosis

 

 Yes

11 (30.6)

 No

25 (69.4)

  1. Data are median (range) or n (%)
  2. CA carbohydrate antigen, CEA carcinoembryonic antigen, ECOG Eastern Cooperative Oncology Group, MSI microsatellite instability, MSS microsatellite stability, PD-L1 programmed death-ligand 1, TBIL total bilirubin, TMB tumor mutational burden, TNM tumor-node-metastasis