Table 1 Application of the BLDM model and ultrasonography in identifying MTN and BTN samples
From: Blood leukocytes as a non-invasive diagnostic tool for thyroid nodules: a prospective cohort study
(%) | Validation cohort | Independent test cohort | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|  |  > 10 mm |  ≤ 10 mm |  |  > 10 mm |  ≤ 10 mm | |||||||
BLDM | US | BLDM | US | BLDM | US | BLDM | US | BLDM | US | BLDM | US | |
Sensitivity | 83.33 | 97.62 | 66.67 | 83.33 | 86.11 | 100 | 82.86 | 100.00 | 75.00 | 100.00 | 83.87 | 100.00 |
Specificity | 90.91 | 43.64 | 90.00 | 57.50 | 93.33 | 6.67 | 88.68 | 47.17 | 85.71 | 67.86 | 92.00 | 24.00 |
Accuracy | 87.63 | 67.01 | 86.96 | 60.87 | 88.24 | 72.55 | 86.36 | 68.18 | 84.38 | 71.88 | 87.50 | 66.07 |
PPV | 87.50 | 56.94 | 50.00 | 22.73 | 96.88 | 72.00 | 82.86 | 55.56 | 42.86 | 30.77 | 92.86 | 62.00 |
NPV | 87.72 | 96.00 | 94.74 | 95.83 | 73.68 | 100.00 | 88.68 | 100.00 | 96.00 | 100.00 | 82.14 | 100.00 |
AUC | 0.86 | 0.85 | 0.87 | 0.87 | 0.86 | 0.65 | 0.86 | 0.82 | 0.87 | 0.98 | 0.86 | 0.68 |