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Table 5 IRR: one-way sensitivity analyses

From: Estimating the returns to UK publicly funded cancer-related research in terms of the net value of improved health outcomes

Analysis

IRR, %

Base casea

10.1

Research funding estimate

 

  Low

10.8

  High

8.7

‘Value’ of a QALY, GB£

 

  20,000

8.0

  30,000

11.7

  50,000

16.1

  70,000

18.9

Elapsed time, years

 

  10

14.6

  20

7.4

Attribution to UK research, %

 

  10

6.1

  25

13.0

Effect of smoking cessation

 

  Decrease NMB by 25%

8.7

  Increase NMB by 25%

11.2

  Omitting benefit of smoking reduction

2.4

  1. Abbreviations: IRR internal rate of return, NMB net monetary benefits, QALY quality adjusted life year.
  2. aBest estimate for research funding and net monetary benefit, QALY value of £25,000, elapsed time of 15 years, and attribution to UK research of 17%).